Detalhe da pesquisa
1.
2-Oxoglutarate-Dependent Oxygenases.
Annu Rev Biochem
; 87: 585-620, 2018 06 20.
Artigo
Inglês
| MEDLINE | ID: mdl-29494239
2.
A code for RanGDP binding in ankyrin repeats defines a nuclear import pathway.
Cell
; 157(5): 1130-45, 2014 May 22.
Artigo
Inglês
| MEDLINE | ID: mdl-24855949
3.
Synthesis of meta-substituted arene bioisosteres from [3.1.1]propellane.
Nature
; 611(7937): 721-726, 2022 11.
Artigo
Inglês
| MEDLINE | ID: mdl-36108675
4.
NADP(H)-dependent biocatalysis without adding NADP(H).
Proc Natl Acad Sci U S A
; 120(1): e2214123120, 2023 01 03.
Artigo
Inglês
| MEDLINE | ID: mdl-36574703
5.
MeDBA: the Metalloenzyme Data Bank and Analysis platform.
Nucleic Acids Res
; 51(D1): D593-D602, 2023 01 06.
Artigo
Inglês
| MEDLINE | ID: mdl-36243971
6.
Studies on enmetazobactam clarify mechanisms of widely used ß-lactamase inhibitors.
Proc Natl Acad Sci U S A
; 119(18): e2117310119, 2022 05 03.
Artigo
Inglês
| MEDLINE | ID: mdl-35486701
7.
Widespread hydroxylation of unstructured lysine-rich protein domains by JMJD6.
Proc Natl Acad Sci U S A
; 119(32): e2201483119, 2022 08 09.
Artigo
Inglês
| MEDLINE | ID: mdl-35930668
8.
Interactions of hydrolyzed ß-lactams with the L1 metallo-ß-lactamase: Crystallography supports stereoselective binding of cephem/carbapenem products.
J Biol Chem
; 299(5): 104606, 2023 05.
Artigo
Inglês
| MEDLINE | ID: mdl-36924941
9.
Natural and synthetic 2-oxoglutarate derivatives are substrates for oncogenic variants of human isocitrate dehydrogenase 1 and 2.
J Biol Chem
; 299(2): 102873, 2023 02.
Artigo
Inglês
| MEDLINE | ID: mdl-36621625
10.
Activity-based proteomics uncovers suppressed hydrolases and a neo-functionalised antibacterial enzyme at the plant-pathogen interface.
New Phytol
; 241(1): 394-408, 2024 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-36866975
11.
Selective targeting of human TET1 by cyclic peptide inhibitors: Insights from biochemical profiling.
Bioorg Med Chem
; 99: 117597, 2024 Feb 01.
Artigo
Inglês
| MEDLINE | ID: mdl-38262305
12.
Photoaffinity labelling displacement assay using multiple recombinant protein domains.
Biochem J
; 480(15): 1183-1197, 2023 Aug 16.
Artigo
Inglês
| MEDLINE | ID: mdl-37401534
13.
Mechanisms of substrate recognition and N6-methyladenosine demethylation revealed by crystal structures of ALKBH5-RNA complexes.
Nucleic Acids Res
; 50(7): 4148-4160, 2022 04 22.
Artigo
Inglês
| MEDLINE | ID: mdl-35333330
14.
Characterization of the SARS-CoV-2 ExoN (nsp14ExoN-nsp10) complex: implications for its role in viral genome stability and inhibitor identification.
Nucleic Acids Res
; 50(3): 1484-1500, 2022 02 22.
Artigo
Inglês
| MEDLINE | ID: mdl-35037045
15.
Combined proteomic and biochemical analyses redefine the consensus sequence requirement for epidermal growth factor-like domain hydroxylation.
J Biol Chem
; 298(8): 102129, 2022 08.
Artigo
Inglês
| MEDLINE | ID: mdl-35700824
16.
Spectroscopic studies reveal details of substrate-induced conformational changes distant from the active site in isopenicillin N synthase.
J Biol Chem
; 298(9): 102249, 2022 09.
Artigo
Inglês
| MEDLINE | ID: mdl-35835215
17.
Factor inhibiting HIF can catalyze two asparaginyl hydroxylations in VNVN motifs of ankyrin fold proteins.
J Biol Chem
; 298(6): 102020, 2022 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35537551
18.
Structural basis for binding of the renal carcinoma target hypoxia-inducible factor 2α to prolyl hydroxylase domain 2.
Proteins
; 91(11): 1510-1524, 2023 11.
Artigo
Inglês
| MEDLINE | ID: mdl-37449559
19.
Tautomer-Specific Deacylation and Ω-Loop Flexibility Explain the Carbapenem-Hydrolyzing Broad-Spectrum Activity of the KPC-2 ß-Lactamase.
J Am Chem Soc
; 145(13): 7166-7180, 2023 04 05.
Artigo
Inglês
| MEDLINE | ID: mdl-36972204
20.
Biochemical and Structural Insights into FIH-Catalysed Hydroxylation of Transient Receptor Potential Ankyrin Repeat Domains.
Chembiochem
; 24(4): e202200576, 2023 02 14.
Artigo
Inglês
| MEDLINE | ID: mdl-36448355